Find at least one human cell line that is commercially available, with a homozygous deletion of the whole tp53 gene or at least of the second and third exon. Send me the name of the cell line along with the publication/data confirming the homozygous deletion.
Some cell lines have conflicting data, I cannot use those.
Some valuable resources:
COSMIC database,
TCGA CCL project,
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Some candidates that I have found: Hep3B, KATO-III, NCI-H1299, H-358, Calu-1, Saos-2 , LN-308, HL-60, EU-4, HTB-10, CLR-1435, HTB-24
Hello! I think that I can help you with your project... I'm a molecular biologist from Argentina...
In the post you say that you've already found some candidates.. what happened with them?
Do you want to get all of the results which have the deletion, some of them, only one?
Given that there have to be a publication confirming the deletion, couldn't be a better approach to directly research pubmed?
Message me if you are interested... and tell me a little more about your job.
Good luck with it!
€100 EUR v 3 dnech
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2 freelanceři nabízejí v průměru €65 EUR za tuto práci
your project will be an amazing project after i have gone through the project details and i will be glad to work on this and i can assure you a total success timely on this project